Endometrial Hyperplasia, Intrauterine (uterine) Thickening, Uterine Wall Thickening

ENDOMETRIAL HYPERPLASIA, UTERINE THICKENING, UTERINE WALL THICKENING

What is endometrium?

The endometrium is the tissue of the inner wall of the uterus that provides menstruation. It is renewed every month with bleeding. Its thickness is controlled by the hormones estrogen and progesterone. If the estrogen hormone is high, the endometrium thickens.

What is Intrauterine Thickening?

It is a thickening of the endometrial tissue in the uterus. This thickening is irregular. The pathologic diagnosis can be simple endometrial thickening or complex endometrial thickening. 

What causes intrauterine thickening?

Age, obesity, never having given birth, genetic causes, estrogen secreting tumors, diabetes, hormone therapy, intrauterine polyps, intrauterine fibroids.

Intrauterine thickening is more common before and after menopause. 

What complaints does intrauterine thickening (endometrial hyperplasia) cause?

The most important symptom is abnormal uterine bleeding. bleeding will be frequent, irregular, profuse. There may be intermittent bleeding or spotting. But sometimes there may be no symptoms at all. Therefore, annual check-ups should be done. 

Bleeding may be accompanied by pain.

How is intrauterine thickening diagnosed?

It is diagnosed in patients with abnormal uterine bleeding or during annual check-ups. The diagnosis is made by taking a pipel endometrial biopsy (taking an intrauterine piece of the uterus) during the examination of patients suspected by ultrasound and pathologic evaluation. In other words, the definitive diagnosis is made by pathologic evaluation of the sample taken. No diagnosis is made without pathology. 

Does intrauterine thickening cause cancer?

If intrauterine thickening is left untreated, it can turn into cancer. So you are at risk of intrauterine cancer. Especially if it is a complex type, the risk of cancer increases. 

How is intrauterine thickening treated?

After the pathologic diagnosis, the type of thickening is important. If it is a simple type, the patient is followed up if she is young, planning to give birth and has no history of other cancers. Progesterone treatment is started and pipel endometrial sampling is performed at 6-month intervals. When it improves pathologically, it is followed up normally.

However, if the endometrial hyperplasia is complex, advanced age, menopause, not planning pregnancy, complete removal of the uterus is recommended because of the high risk of cancer. But these patients can be followed up with endometrial pipel sampling at 3-month intervals. We do not recommend this treatment.

What is Pipel Endometrial sampling and how is it performed?

It is done to evaluate the inside of the uterus, i.e. the andometrium. The sample is sent to pathology. It provides a definitive diagnosis. 

After the cervix is anesthetized, it is performed with a special catheter under examination conditions, without hospitalization. It is a simple and safe procedure. You can continue your daily life after the procedure. There is no need to rest. Rarely, in our patients who are afraid and have impaired pain tolerance, the procedure is performed under examination conditions or in the hospital by simply anesthetizing them. It is not a scary procedure.

What should be the intra-uterine thickness?

 Endometrial thickness should be 5 mm or less after menopause and 8 mm or less during reproductive age.

Where can I get treatment for intrauterine thickening?

Uterine wall thickening treatment and uterine sampling are performed by Assoc. Prof. Dr. Osman Temizkan in Istanbul . For detailed information about the treatment of uterine wall thickening, you can contact us on +90 533 899 45 32.

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