Ovarian Aging, Ovarian Failure, Early Menopause, Ovarian Reserve

Ovarian Aging, Ovarian Failure, Ovarian Reserve Nisantasi, Istanbul

What is ovarian aging or premature ovarian aging?

Low ovarian reserve for a woman's age and low number of good quality eggs. It is the most important cause of infertility.

What are the symptoms of ovarian aging?

There may be no symptoms. Menstrual irregularity and menopausal symptoms may be absent. They usually complain of inability to conceive. However, they are diagnosed incidentally during routine controls. Therefore, patients should be evaluated for ovarian reserve during routine controls.

When does ovarian aging occur?

It can occur at any age, but the frequency increases especially around the age of 35. 

What is ovarian reserve?

Ovarian reserve is the number of follicles in the ovaries, i.e. the number of eggs and egg quality. Appropriate hormonal influence and age affect ovarian function. It is the most important factor affecting the chances of conception, i.e. reproductive potential. There are few or no good quality eggs transferred.

In low ovarian reserve, the number and quality of eggs are poor. They are patients who respond poorly to treatment or do not respond to treatment.

Ovarian reserve should be assessed in every patient with infertility. This determines the chances of conception.

How is ovarian reserve assessed?

Determining ovarian reserve is easy.

Normal ovarian reserve requires normal hormonal function. When ovarian reserve is impaired, hormonal function is disrupted. Menstrual cycle is disrupted. 

For ovarian reserve, hormonal evaluation (such as FSH test, LH test, E2 test), ultrasonographic follicle count determination, AMH (anti-millerian hormone) evaluation are performed. The reserve is determined according to these results.

What is the AMH Test?

The AMH test is used to assess ovarian reserve. In other words, it is an assessment of fertility. If the AMH test is low, the number and quality of eggs is low. But evaluating it alone may cause wrong results. It should be done together with other tests.

What are the causes affecting ovarian reserve?

The most important factors affecting ovarian reserve are genetics and age.

What is premature ovarian failure (early menopause, premature ovarian failure)?

Ovarian failure is when ovarian function ends before the age of 40 and the patient enters menopause. These patients have very little chance of becoming pregnant. Rarely, with some treatments, ovarian function can be restored and the patient has a chance to become pregnant. 

What are the causes of early ovarian failure (early menopause)?

Familial (hereditary) causes are important. most of these patients have a mother or aunt with early menopause. Some chromosomal diseases, such as fragile x syndrome, turner syndrome, mumps, pelvic infections, smoking, chemotherapy, radiotherapy, ovarian surgery, autoimmune diseases can cause early ovarian failure. Sometimes no cause can be found. 

How is the egg reserve in the ovary normally?

The most important factor is age. Especially after the age of 35, the number of eggs and egg quality start to decrease and the decrease accelerates even more after the age of 40. Around the age of 50-55, the eggs in the ovaries run out and the person enters menopause. Reproductive functions end.

Sometimes this is not the case and ovarian aging occurs at an earlier age. For this reason, those who plan to have a baby later should evaluate their ovarian reserve with regular controls. They should get an answer to the question of whether I can conceive or how is my egg reserve.

How often and when should I start assessing ovarian reserve?

It is appropriate to have an ovarian reserve assessment every year. Your ovarian reserve will also be evaluated during your annual gynecological check-ups. However, if there is early menopause in your family, it should be started at an early age and strict follow-up should be done.

In our clinic, ovarian reserve and ovarian failure are examined in detail by Assoc Prof Osman Temizkan and Op Dr Bülent Arıcı. If necessary, egg freezing and IVF planning and treatment are performed.

What should be done in case of ovarian failure and poor egg reserve? 

Egg freezing should be planned in case of early ovarian failure and poor ovarian reserve. Egg freezing preserves the chance of pregnancy. The collected eggs are stored for 5 years. 

infertility, ovarian failure, ovarian aging, premature ovarian failure, premature menopause, premature ovarian failure, ovarian failure, ovarian reserve, ovarian reserve, Doc Dr Osman Temizkan. Op Dr Bülent Arıcı

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